DFFBP1

Across TCGA patient cohorts, DFFBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,128 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible DFFBP1-associated GO terms across cancer lineages are RNA export from nucleus, RNA modification, and Nuclear-transcribed mRNA catabolic process. Each is linked with DFFBP1 in more than 32 cancer types. Because this analysis shows association rather than direction, both DFFBP1-to-partner and partner-to-DFFBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by DFFBP1-low versus DFFBP1-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DFFBP1→partner) and Y-score (partner→DFFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	RNA export from nucleus →	+0.063	+0.692	<.001	<.001	3	33
STAD	RNA modification →	+0.045	+0.269	<.001	<.001	3	32
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.061	+0.469	<.001	<.001	3	32
UCS	Cytoplasmic translational initiation →	+0.078	+0.602	<.001	<.001	3	32
ESCA	miRNA processing →	+0.059	+0.320	<.001	<.001	3	32
UCS	Positive regulation of RNA export from nucleus →	+0.073	+0.787	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,128 associations by consensus.

RNA export from nucleus by DFFBP1 expression — UCS

Explore this box plot interactively →