DNA fragmentation factor subunit beta pseudogene 1Genealiases: []
Q-omics provides the consensus-scored DFFBP1 profile across patient tissues and cancer cell-line models. DFFBP1 expression is associated with patient survival in 28 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, DFFBP1 is differentially expressed in 9, with the highest sampling consensus in THCA. Additionally, DFFBP1 RNA expression shows 18,506 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, THCA, and UVM as cancer lineages where DFFBP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DFFBP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DFFBP1 survival associations across molecular data types. DFFBP1 RNA expression shows survival associations in the most cancer types (28). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DFFBP1 RNA expression–survival associations across cancer types. High DFFBP1 expression shows unfavorable associations in ACC, UVM, LIHC and UCEC, but favorable associations in BRCA and UCS. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for DFFBP1 RNA expression.
This table summarizes DFFBP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for DFFBP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DFFBP1 shows lower tumor expression in THCA and BRCA and higher tumor expression in HNSC, LIHC, UCEC and STAD. The THCA box plot shows higher DFFBP1 RNA expression in normal versus tumor tissue (log2 FC = −0.420, t-test p < 0.001).
This table shows molecular features associated with DFFBP1 in patient tissues and cancer cell lines. In patient samples, DFFBP1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
