DFFA

Across TCGA patient cohorts, DFFA RNA expression is significantly associated with the protein abundance of many other proteins, with 14,386 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DFFA-associated proteins across cancer lineages are WRNIP1, THOC1, and THOC5. Each is linked with DFFA in more than 6 cancer types. Because this analysis shows association rather than direction, both DFFA-to-partner and partner-to-DFFA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DFFA versus WRNIP1 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DFFA→partner) and Y-score (partner→DFFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WRNIP1 →	+0.338	+0.476	<.001	<.001	3	7
LSCC	THOC1 →	+0.334	+0.575	<.001	<.001	3	6
LSCC	THOC5 →	+0.317	+0.548	<.001	<.001	3	6
OV	LRRC47 →	+0.385	+0.667	<.001	<.001	3	6
OV	LZIC →	+0.488	+0.813	<.001	<.001	3	6
OV	USP48 →	+0.385	+0.557	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,386 associations by consensus.

DFFA vs WRNIP1 — LSCC

Explore this scatter interactively →