DEUP1

Across TCGA patient cohorts, DEUP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,232 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DEUP1-associated proteins across cancer lineages are CCDC186, CDK12_S681, and RIN1. Each is linked with DEUP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DEUP1-to-partner and partner-to-DEUP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEUP1 versus CCDC186 in HNSC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEUP1→partner) and Y-score (partner→DEUP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCDC186 →	-0.300	-0.695	<.001	<.001	3	4
BRCA	CDK12_S681 →	-0.463	-0.375	<.001	<.001	3	4
LSCC	RIN1 →	-0.622	-0.720	<.001	<.001	3	3
LUAD	RPL5 →	-0.195	-0.440	.001	<.001	3	3
LSCC	MAP1LC3A →	+0.642	+0.532	.001	.005	3	3
LSCC	MAP2 →	+0.720	+0.626	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,232 associations by consensus.

DEUP1 vs CCDC186 — HNSC

Explore this scatter interactively →