DESI1

Across TCGA patient cohorts, DESI1 RNA expression is significantly associated with the RNA expression of many other genes, with 18,401 significant associations in total. ACC shows the largest number of these associations.

The most reproducible DESI1-associated genes across cancer lineages are TCF20, MIEF1, and ZBED4. Each is linked with DESI1 in more than 31 cancer types. Because this analysis shows association rather than direction, both DESI1-to-partner and partner-to-DESI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DESI1 versus TCF20 in ACC, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DESI1→partner) and Y-score (partner→DESI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	TCF20 →	+1.166	+1.056	<.001	<.001	3	32
ACC	MIEF1 →	+1.357	+1.154	<.001	<.001	3	32
ACC	ZBED4 →	+1.147	+1.021	<.001	<.001	3	31
ACC	SREBF2 →	+1.672	+1.002	<.001	<.001	3	31
ACC	TTLL12 →	+1.746	+1.067	<.001	<.001	3	31
THYM	ZC3H7B →	+1.386	+0.400	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,401 associations by consensus.

DESI1 vs TCF20 — ACC

Explore this scatter interactively →