DESI1

Across TCGA patient cohorts, DESI1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,796 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DESI1-associated proteins across cancer lineages are ZC3H7B, EIF4ENIF1, and MIEF1_S59. Each is linked with DESI1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DESI1-to-partner and partner-to-DESI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DESI1 versus ZC3H7B in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DESI1→partner) and Y-score (partner→DESI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZC3H7B →	+0.296	+0.561	<.001	<.001	3	8
GBM	EIF4ENIF1 →	+0.346	+0.418	<.001	<.001	3	7
OV	MIEF1_S59 →	+0.880	+0.429	<.001	.002	3	7
BRCA	ATXN10 →	+0.434	+0.528	<.001	<.001	3	6
OV	GTPBP1 →	+0.281	+0.393	<.001	<.001	3	6
HNSC	MIEF1 →	+0.305	+0.762	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,796 associations by consensus.

DESI1 vs ZC3H7B — OV

Explore this scatter interactively →