DESI1

Across TCGA patient cohorts, DESI1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,916 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DESI1-associated genes across cancer lineages are FAM174B, MICALL1, and PKIG. Each is linked with DESI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DESI1-to-partner and partner-to-DESI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DESI1 versus FAM174B in BRCA, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DESI1→partner) and Y-score (partner→DESI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM174B →	-0.955	-0.393	.001	.002	3	5
OV	MICALL1 →	+0.886	+0.525	.004	.001	3	5
HNSC	PKIG →	-0.670	-0.326	.001	.008	3	5
UCEC	WDR93 →	-0.951	-0.400	.001	.001	3	4
OV	SNU13 →	+0.732	+0.690	<.001	<.001	3	4
BRCA	TOMM22 →	+0.541	+0.571	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,916 associations by consensus.

DESI1 vs FAM174B — BRCA

Explore this scatter interactively →