DERL2

Across TCGA patient cohorts, DERL2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,758 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DERL2-associated genes across cancer lineages are ILVBL, ZNF823, and ARL2BP. Each is linked with DERL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both DERL2-to-partner and partner-to-DERL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DERL2 versus ILVBL in UCEC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DERL2→partner) and Y-score (partner→DERL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ILVBL →	-1.163	-0.795	<.001	<.001	3	5
HNSC	ZNF823 →	-0.819	-0.502	.006	<.001	3	4
LSCC	ARL2BP →	-0.678	-0.361	<.001	.003	3	3
HNSC	TMCO6 →	-0.634	-0.332	.002	.003	3	3
HNSC	GIPC1 →	-1.257	-0.543	<.001	<.001	3	3
UCEC	DOHH →	-1.131	-0.606	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,758 associations by consensus.

DERL2 vs ILVBL — UCEC

Explore this scatter interactively →