DERA

Across TCGA patient cohorts, DERA protein abundance is significantly associated with the RNA expression of many other genes, with 15,483 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DERA-associated genes across cancer lineages are ALDH16A1, ACTR3B, and FMC1. Each is linked with DERA in more than 6 cancer types. Because this analysis shows association rather than direction, both DERA-to-partner and partner-to-DERA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DERA versus ALDH16A1 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DERA→partner) and Y-score (partner→DERA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ALDH16A1 →	+0.945	+0.455	<.001	<.001	3	7
LSCC	ACTR3B →	-0.556	-0.241	<.001	.002	3	5
GBM	FMC1 →	-0.397	-0.256	<.001	.001	3	5
GBM	KLHL23 →	-1.076	-0.388	<.001	<.001	3	5
GBM	JADE3 →	-0.875	-0.306	<.001	<.001	3	4
GBM	TUBB4A →	-1.204	-0.185	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,483 associations by consensus.

DERA vs ALDH16A1 — OV

Explore this scatter interactively →