DEPDC5

Across TCGA patient cohorts, DEPDC5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,465 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DEPDC5-associated genes across cancer lineages are SLN, ANKRD54, and HSCB. Each is linked with DEPDC5 in more than 2 cancer types. Because this analysis shows association rather than direction, both DEPDC5-to-partner and partner-to-DEPDC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPDC5 versus SLN in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC5→partner) and Y-score (partner→DEPDC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLN →	+2.635	+0.359	.002	<.001	3	3
HNSC	ANKRD54 →	+0.479	+0.219	.002	.004	3	3
BRCA	HSCB →	+0.530	+0.314	<.001	<.001	3	3
COAD	SRPX →	+1.853	+1.430	<.001	<.001	3	2
COAD	SFRP1 →	+2.150	+1.241	<.001	<.001	3	2
COAD	C7 →	+2.821	+1.062	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,465 associations by consensus.

DEPDC5 vs SLN — HNSC

Explore this scatter interactively →