DEPDC4

Across TCGA patient cohorts, DEPDC4 RNA expression is significantly associated with the RNA expression of many other genes, with 19,609 significant associations in total. UVM shows the largest number of these associations.

The most reproducible DEPDC4-associated genes across cancer lineages are PWP1, ANAPC7, and GTF2H3. Each is linked with DEPDC4 in more than 33 cancer types. Because this analysis shows association rather than direction, both DEPDC4-to-partner and partner-to-DEPDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPDC4 versus PWP1 in ACC, with a Pearson correlation of 0.65.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC4→partner) and Y-score (partner→DEPDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	PWP1 →	+0.808	+0.392	<.001	<.001	3	34
UVM	ANAPC7 →	+0.781	+0.408	<.001	<.001	3	33
UVM	GTF2H3 →	+1.416	+0.409	<.001	<.001	3	33
UVM	SCYL2 →	+1.407	+0.377	<.001	<.001	3	33
UVM	ACTR6 →	+1.232	+0.412	<.001	<.001	3	33
UVM	PTCD3 →	+1.341	+0.376	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,609 associations by consensus.

DEPDC4 vs PWP1 — ACC

Explore this scatter interactively →