DEPDC1B

Across TCGA cell cohorts, DEPDC1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,126 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DEPDC1B-associated GO terms across cancer lineages are Kinetochore assembly, Kinetochore organization, and Replication fork processing. Each is linked with DEPDC1B in more than 18 cancer types. Because this analysis shows association rather than direction, both DEPDC1B-to-partner and partner-to-DEPDC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Kinetochore assembly grouped by DEPDC1B-low versus DEPDC1B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC1B→partner) and Y-score (partner→DEPDC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Kinetochore assembly →	+0.165	+0.989	<.001	<.001	3	19
OESOPHAGUS	Kinetochore organization →	+0.166	+0.989	<.001	<.001	3	19
OESOPHAGUS	Replication fork processing →	+0.162	+1.525	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid segregation →	+0.128	+1.576	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Spindle organization →	+0.081	+1.268	.001	<.001	3	17
BREAST	Mitotic spindle organization →	+0.105	+1.169	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,126 associations by consensus.

Kinetochore assembly by DEPDC1B expression — OESOPHAGUS

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