DEPDC1

Across TCGA patient cohorts, DEPDC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,070 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DEPDC1-associated proteins across cancer lineages are PTPN2_S304, PURA, and UFD1_S247. Each is linked with DEPDC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DEPDC1-to-partner and partner-to-DEPDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPDC1 versus PTPN2_S304 in LUAD, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC1→partner) and Y-score (partner→DEPDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PTPN2_S304 →	+0.824	+1.178	<.001	<.001	3	10
BRCA	PURA →	-0.427	-1.089	<.001	<.001	3	10
LUAD	UFD1_S247 →	+0.822	+1.181	<.001	<.001	3	10
LUAD	NCAPG_S674 →	+1.370	+1.379	<.001	<.001	3	10
LUAD	NCL_S67 →	+1.138	+1.309	<.001	<.001	3	10
LUAD	NPM1_T199 →	+1.905	+0.898	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,070 associations by consensus.

DEPDC1 vs PTPN2_S304 — LUAD

Explore this scatter interactively →