DEPDC1

Across TCGA patient cohorts, DEPDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,877 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEPDC1-associated genes across cancer lineages are NT5DC3, COL7A1, and CXCL14. Each is linked with DEPDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEPDC1-to-partner and partner-to-DEPDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEPDC1 versus NT5DC3 in HNSC, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC1→partner) and Y-score (partner→DEPDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NT5DC3 →	-0.799	-0.782	.002	.009	3	1
HNSC	COL7A1 →	+1.044	+0.782	.006	.009	3	1
HNSC	CXCL14 →	+2.732	+0.782	.003	.009	3	1
HNSC	ERMAP →	-0.946	-0.782	.001	.009	3	1
HNSC	ZBTB34 →	-0.670	-0.782	.008	.009	3	1
HNSC	MAF →	+0.939	+0.782	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,877 associations by consensus.

DEPDC1 vs NT5DC3 — HNSC

Explore this scatter interactively →