DEPDC1

Across TCGA cell cohorts, DEPDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,386 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DEPDC1-associated GO terms across cancer lineages are Nuclear chromosome segregation, Mitotic spindle assembly checkpoint signaling, and Spindle assembly checkpoint signaling. Each is linked with DEPDC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both DEPDC1-to-partner and partner-to-DEPDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear chromosome segregation grouped by DEPDC1-low versus DEPDC1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEPDC1→partner) and Y-score (partner→DEPDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Nuclear chromosome segregation →	+0.130	+1.397	<.001	<.001	3	20
OESOPHAGUS	Mitotic spindle assembly checkpoint signaling →	+0.150	+0.993	<.001	<.001	3	20
OESOPHAGUS	Spindle assembly checkpoint signaling →	+0.150	+0.993	<.001	<.001	3	20
OESOPHAGUS	Mitotic spindle checkpoint signaling →	+0.150	+0.993	<.001	<.001	3	20
BLOOD_Myeloma	Positive regulation of cell cycle process →	+0.115	+1.823	<.001	<.001	3	20
PANCREAS	Spindle elongation →	+0.293	+1.177	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,386 associations by consensus.

Nuclear chromosome segregation by DEPDC1 expression — PANCREAS

Explore this box plot interactively →