DEPDC1-AS1

Across TCGA pan-cancer cohorts, DEPDC1-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated DEPDC1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher DEPDC1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DEPDC1-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and THYM show a favorable association.

MESO, KICH, and ACC are the cancer types where DEPDC1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.387	0.670	<.001	120	view →
KICH	DFS	Quartile	All	0.609	0.959	<.001	80	view →
ACC	OS	Median	All	0.761	0.974	<.001	70	view →
LIHC	DFS	Median	All	0.370	0.496	<.001	63	view →
KIRC	OS	Tertile	All	0.740	0.834	.005	51	view →
PAAD	OS	Median	All	0.267	0.499	<.001	50	view →
LGG	DFS	Median	All	0.777	0.880	<.001	49	view →
UCEC	DFS	Quartile	All	0.770	0.882	.003	40	view →
OV	DFS	Median	III,IV	0.207	0.113	.002	38	view →
LUAD	OS	Quartile	All	0.714	0.819	.009	34	view →
BLCA	OS	Quartile	All	0.618	0.814	<.001	33	view →
KIRP	OS	Tertile	All	0.530	0.790	<.001	31	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

DEPDC1-AS1–MESO (OS)

Open the MESO breakdown →