DEPDC1-AS1

Across TCGA pan-cancer cohorts, DEPDC1-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of DEPDC1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DEPDC1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DEPDC1-AS1 is over-expressed in tumor.

HNSC, KIRP, and KIRC are the cancer types where DEPDC1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DEPDC1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.289	<.001	10	view →
KIRP	All	III,IV	+0.059	<.001	9	view →
KIRC	All	II,III,IV	+0.054	<.001	9	view →
UCEC	All	III,IV	+0.605	<.001	8	view →
LUSC	Female	All	+0.265	<.001	7	view →
LUAD	Male	II,III,IV	+0.217	<.001	7	view →
BRCA	All	II,III,IV	+0.191	<.001	6	view →
COAD	All	All	+0.173	.001	6	view →
STAD	All	All	+0.171	.001	6	view →
BLCA	All	All	+0.141	.023	5	view →
ESCA	Female	All	+0.196	.001	4	view →
LIHC	Male	All	+0.104	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

DEPDC1-AS1–HNSC

Open the HNSC breakdown →