Across TCGA cell cohorts, DENND6B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,511 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DENND6B-associated GO terms across cancer lineages are Flagellated sperm motility, Cilium movement involved in cell motility, and Process utilizing autophagic mechanism. Each is linked with DENND6B in more than 14 cancer types. Because this analysis shows association rather than direction, both DENND6B-to-partner and partner-to-DENND6B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND6B→partner) and Y-score (partner→DENND6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Flagellated sperm motility →	-0.123	-1.066	.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.103	-0.873	<.001	<.001	3	15
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.073	+1.126	<.001	<.001	3	15
OESOPHAGUS	Autophagy →	+0.073	+1.126	<.001	<.001	3	15
OESOPHAGUS	Sperm motility →	-0.123	-1.066	.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.099	-0.873	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,511 associations by consensus.

Exploration

DENND6B survival (RNA) · tumor vs normal (RNA) · all DENND6B data types