DENND6A-DT

Across TCGA patient cohorts, DENND6A-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,891 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DENND6A-DT-associated GO terms across cancer lineages are Regulation of microtubule-based process, Methylation, and DNA-templated DNA replication maintenance of fidelity. Each is linked with DENND6A-DT in more than 19 cancer types. Because this analysis shows association rather than direction, both DENND6A-DT-to-partner and partner-to-DENND6A-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule-based process grouped by DENND6A-DT-low versus DENND6A-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND6A-DT→partner) and Y-score (partner→DENND6A-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of microtubule-based process →	+0.047	+0.120	<.001	<.001	3	20
STAD	Methylation →	+0.055	+0.124	<.001	<.001	3	19
STAD	DNA-templated DNA replication maintenance of fidelity →	+0.054	+0.104	<.001	<.001	3	18
ESCA	DNA replication →	+0.074	+0.126	<.001	.005	3	18
STAD	DNA strand elongation →	+0.063	+0.103	<.001	<.001	3	18
STAD	mRNA 3'-end processing →	+0.064	+0.103	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,891 associations by consensus.

Regulation of microtubule-based process by DENND6A-DT expression — STAD

Explore this box plot interactively →