DENND5B-AS1

Across TCGA patient cohorts, DENND5B-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DENND5B-AS1-associated proteins across cancer lineages are DENND5B_T1062, ARFIP1, and PTPN3. Each is linked with DENND5B-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DENND5B-AS1-to-partner and partner-to-DENND5B-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DENND5B-AS1 versus DENND5B_T1062 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND5B-AS1→partner) and Y-score (partner→DENND5B-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DENND5B_T1062 →	+0.590	+0.404	<.001	.001	3	4
BRCA	ARFIP1 →	-0.308	-0.387	<.001	.004	3	4
UCEC	PTPN3 →	-0.337	-0.405	<.001	<.001	3	3
BRCA	PPP2CB →	-0.665	-0.495	<.001	<.001	3	3
LUAD	MUC1 →	-0.697	-0.599	<.001	<.001	3	3
GBM	S100A8 →	-1.027	-0.330	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,222 associations by consensus.

DENND5B-AS1 vs DENND5B_T1062 — LUAD

Explore this scatter interactively →