DEK

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEK RNA expression is significantly associated with the protein abundance of many other proteins, with 17,503 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DEK-associated proteins across cancer lineages are DAXX, DHX16, and MCM3. Each is linked with DEK in more than 8 cancer types. Because this analysis shows association rather than direction, both DEK-to-partner and partner-to-DEK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEK versus DAXX in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEK→partner) and Y-score (partner→DEK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDAXX →+0.368+0.830<.001<.00139
OVDHX16 →+0.272+0.656<.001<.00139
LUADMCM3 →+0.733+0.489<.001<.00139
LUADMCM4 →+0.732+0.501<.001<.00139
LUADMCM5 →+0.695+0.501<.001<.00139
LUADMCM7 →+0.703+0.501<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,503 associations by consensus.

DEK vs DAXX — OV

Per-sample scatter of DEK vs DAXX in OV (Pearson r = 0.47).

Explore this scatter interactively →

Exploration