DEGS1

Across TCGA patient cohorts, DEGS1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEGS1-associated genes across cancer lineages are cDC, Adipocytes, and pDC. Each is linked with DEGS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEGS1-to-partner and partner-to-DEGS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cDC grouped by DEGS1-low versus DEGS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEGS1→partner) and Y-score (partner→DEGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cDC →	+0.137	+3.008	.001	.019	3	1
UCEC	Adipocytes →	+0.028	+2.337	.002	.010	3	1
UCEC	pDC →	+0.077	+2.815	.002	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

cDC by DEGS1 expression — UCEC

Explore this box plot interactively →