DEGS1

Across TCGA cell cohorts, DEGS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,542 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DEGS1-associated GO terms across cancer lineages are Regulation of endoplasmic reticulum tubular network organization, Collagen fibril organization, and Peptidyl-lysine oxidation. Each is linked with DEGS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both DEGS1-to-partner and partner-to-DEGS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endoplasmic reticulum tubular network organization grouped by DEGS1-low versus DEGS1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEGS1→partner) and Y-score (partner→DEGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of endoplasmic reticulum tubular network organization →	+0.092	+0.957	<.001	.002	3	12
LIVER	Collagen fibril organization →	+0.285	+1.303	.005	<.001	2	12
STOMACH	Peptidyl-lysine oxidation →	+1.060	+1.724	<.001	<.001	3	11
KIDNEY	Positive regulation of ATP-dependent activity →	+0.116	+0.868	<.001	<.001	2	11
STOMACH	Regulation of entry of bacterium into host cell →	+0.179	+1.725	<.001	.003	3	9
BONE	External encapsulating structure organization →	+0.232	+0.637	.002	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,542 associations by consensus.

Regulation of endoplasmic reticulum tubular network organization by DEGS1 expression — LUNG_NSCLC_LUAD

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