Across TCGA patient cohorts, DEFB134 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,960 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB134-associated GO terms across cancer lineages are Glucan metabolic process, Obsolete histone modification, and Regulation of protein ubiquitination. Each is linked with DEFB134 in more than 11 cancer types. Because this analysis shows association rather than direction, both DEFB134-to-partner and partner-to-DEFB134 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB134→partner) and Y-score (partner→DEFB134) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Glucan metabolic process →	+0.053	+0.079	<.001	<.001	3	12
STAD	Obsolete histone modification →	+0.058	+0.101	<.001	<.001	3	12
STAD	Regulation of protein ubiquitination →	+0.056	+0.090	<.001	<.001	3	12
STAD	Negative regulation of cytoskeleton organization →	+0.050	+0.073	<.001	<.001	3	12
STAD	Mitochondrial electron transport, cytochrome c to oxygen →	+0.068	+0.065	<.001	<.001	3	12
STAD	Mitochondrial transport →	+0.058	+0.087	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,960 associations by consensus.

Exploration

DEFB134 survival (RNA) · tumor vs normal (RNA) · all DEFB134 data types