DEFB131E

Across TCGA patient cohorts, DEFB131E RNA expression is significantly associated with the RNA expression of many other genes, with 15,075 significant associations in total. UVM shows the largest number of these associations.

The most reproducible DEFB131E-associated genes across cancer lineages are GJC1, TRPC1, and FAM66C. Each is linked with DEFB131E in more than 22 cancer types. Because this analysis shows association rather than direction, both DEFB131E-to-partner and partner-to-DEFB131E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB131E versus GJC1 in KIRC, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB131E→partner) and Y-score (partner→DEFB131E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	GJC1 →	+1.202	+0.615	<.001	<.001	3	23
THYM	TRPC1 →	+1.047	+0.867	<.001	<.001	3	22
UCS	FAM66C →	+1.045	+0.678	<.001	<.001	3	22
ACC	ARHGEF25 →	+1.127	+0.476	.001	.003	2	22
UVM	BRSK1 →	+0.896	+0.256	<.001	.002	2	22
PRAD	RAB9B →	+0.901	+0.707	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,075 associations by consensus.

DEFB131E vs GJC1 — KIRC

Explore this scatter interactively →