Across TCGA cell cohorts, DEFB131B RNA expression is significantly associated with the mutation status of many other genes, with 32 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DEFB131B-associated genes across cancer lineages are ZFHX4, APC, and VIRMA. Each is linked with DEFB131B in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB131B-to-partner and partner-to-DEFB131B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB131B→partner) and Y-score (partner→DEFB131B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ZFHX4 →	+2.754	+0.287	.008	<.001	3	2
SOFT_TISSUE	APC →	+3.977	+0.216	.007	<.001	3	1
SOFT_TISSUE	VIRMA →	+5.977	+0.433	.001	<.001	3	1
SOFT_TISSUE	CTNND2 →	+3.977	+0.216	.007	<.001	3	1
SOFT_TISSUE	ACSL5 →	+5.977	+0.433	.001	<.001	3	1
SOFT_TISSUE	DRD4 →	+4.977	+0.325	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

DEFB131B survival (RNA) · tumor vs normal (RNA) · all DEFB131B data types