Across TCGA pan-cancer cohorts, DEFB131B RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated DEFB131B data layer.
The strongest signal is observed in rectum adenocarcinoma (READ), where higher DEFB131B RNA is associated with better overall survival. In most high-consensus cancer types, elevated DEFB131B expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.
READ, ACC, and SKCM are the cancer types where DEFB131B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.