DEFB130D

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DEFB130D RNA expression is significantly associated with the go_rna of many other GO terms, with 6,414 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB130D-associated GO terms across cancer lineages are Organelle fusion, Protein complex oligomerization, and Protein folding. Each is linked with DEFB130D in more than 7 cancer types. Because this analysis shows association rather than direction, both DEFB130D-to-partner and partner-to-DEFB130D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle fusion grouped by DEFB130D-low versus DEFB130D-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB130D→partner) and Y-score (partner→DEFB130D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADOrganelle fusion →+0.098+0.183<.001<.00138
STADProtein complex oligomerization →+0.079+0.205<.001<.00138
ESCAProtein folding →+0.103+0.160<.001<.00138
ESCAProtein methylation →+0.087+0.160<.001<.00138
STADProtein N-linked glycosylation →+0.090+0.183<.001<.00138
STADProtein targeting to mitochondrion →+0.103+0.203<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,414 associations by consensus.

Organelle fusion by DEFB130D expression — STAD

Box plot of Organelle fusion in DEFB130D-low vs DEFB130D-high samples in STAD.

Explore this box plot interactively →

Exploration