DEFB129

Across TCGA patient cohorts, DEFB129 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,850 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB129-associated GO terms across cancer lineages are Regulation of aerobic respiration, Cellular respiration, and Aerobic respiration. Each is linked with DEFB129 in more than 8 cancer types. Because this analysis shows association rather than direction, both DEFB129-to-partner and partner-to-DEFB129 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of aerobic respiration grouped by DEFB129-low versus DEFB129-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB129→partner) and Y-score (partner→DEFB129) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of aerobic respiration →	+0.102	+0.045	<.001	.001	3	9
STAD	Cellular respiration →	+0.140	+0.050	<.001	<.001	3	7
STAD	Aerobic respiration →	+0.143	+0.048	<.001	<.001	3	6
STAD	Proton transmembrane transport →	+0.111	+0.050	<.001	<.001	3	6
STAD	Oxidative phosphorylation →	+0.149	+0.080	<.001	<.001	3	6
STAD	Monocarboxylic acid biosynthetic process →	+0.058	+0.072	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,850 associations by consensus.

Regulation of aerobic respiration by DEFB129 expression — STAD

Explore this box plot interactively →