DEFB129

Across TCGA patient cohorts, DEFB129 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,591 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DEFB129-associated proteins across cancer lineages are NBEAL1_T906, NEK4_S563, and MYO9A_S1559. Each is linked with DEFB129 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB129-to-partner and partner-to-DEFB129 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB129 versus NBEAL1_T906 in PDAC, with a Pearson correlation of 0.97.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB129→partner) and Y-score (partner→DEFB129) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NBEAL1_T906 →	+2.000	+2.030	<.001	.001	3	2
UCEC	NEK4_S563 →	+1.027	+0.737	<.001	<.001	3	2
CCRCC	MYO9A_S1559 →	-0.566	-0.384	<.001	<.001	3	1
CCRCC	MYO9A_S755 →	-1.083	-0.568	<.001	<.001	3	1
CCRCC	NFIC_S294 →	-0.306	-0.519	.005	.001	3	1
CCRCC	ARHGAP10_T648 →	+0.465	+0.375	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,591 associations by consensus.

DEFB129 vs NBEAL1_T906 — PDAC

Explore this scatter interactively →