DEFB129

Across TCGA patient cohorts, DEFB129 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEFB129-associated genes across cancer lineages are Erythrocytes and Plasma cells. Each is linked with DEFB129 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB129-to-partner and partner-to-DEFB129 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by DEFB129-low versus DEFB129-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB129→partner) and Y-score (partner→DEFB129) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.040	+3.459	.001	.005	3	1
UCEC	Plasma cells →	-0.025	-2.279	.022	.036	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Erythrocytes by DEFB129 expression — UCEC

Explore this box plot interactively →