DEFB129

Across TCGA cell cohorts, DEFB129 RNA expression is significantly associated with the mutation status of many other genes, with 123 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DEFB129-associated genes across cancer lineages are KIAA0100, SYNJ2, and RIF1. Each is linked with DEFB129 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB129-to-partner and partner-to-DEFB129 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIAA0100 grouped by DEFB129-low versus DEFB129-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB129→partner) and Y-score (partner→DEFB129) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KIAA0100 →	+5.247	+0.032	.001	<.001	3	1
BLOOD_Lymphoma	SYNJ2 →	+4.662	+0.026	.003	<.001	3	1
BLOOD_Lymphoma	RIF1 →	+4.247	+0.021	.004	<.001	3	1
BLOOD_Lymphoma	PKP1 →	+5.247	+0.032	.001	<.001	3	1
BLOOD_Lymphoma	FAM135A →	+5.247	+0.032	.001	<.001	3	1
BLOOD_Lymphoma	HACE1 →	+6.247	+0.043	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 123 associations by consensus.

KIAA0100 by DEFB129 expression — BLOOD_Lymphoma

Explore this box plot interactively →