DEFB127

Across TCGA patient cohorts, DEFB127 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,302 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB127-associated GO terms across cancer lineages are Endoplasmic reticulum organization, Protein stabilization, and Positive regulation of amide metabolic process. Each is linked with DEFB127 in more than 7 cancer types. Because this analysis shows association rather than direction, both DEFB127-to-partner and partner-to-DEFB127 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum organization grouped by DEFB127-low versus DEFB127-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB127→partner) and Y-score (partner→DEFB127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Endoplasmic reticulum organization →	+0.103	+0.173	<.001	<.001	3	8
STAD	Protein stabilization →	+0.102	+0.153	<.001	<.001	3	8
STAD	Positive regulation of amide metabolic process →	+0.104	+0.151	<.001	<.001	3	8
STAD	Protein acylation →	+0.098	+0.147	<.001	<.001	3	8
STAD	Mitochondrial gene expression →	+0.113	+0.165	<.001	<.001	3	7
STAD	Negative regulation of proteasomal protein catabolic process →	+0.102	+0.154	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,302 associations by consensus.

Endoplasmic reticulum organization by DEFB127 expression — STAD

Explore this box plot interactively →