DEFB126

Across TCGA patient cohorts, DEFB126 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,613 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB126-associated GO terms across cancer lineages are tRNA 5'-leader removal, Peptidyl-arginine modification, and Mitochondrial translation. Each is linked with DEFB126 in more than 11 cancer types. Because this analysis shows association rather than direction, both DEFB126-to-partner and partner-to-DEFB126 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-leader removal grouped by DEFB126-low versus DEFB126-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB126→partner) and Y-score (partner→DEFB126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA 5'-leader removal →	+0.057	+0.285	<.001	<.001	3	11
STAD	Peptidyl-arginine modification →	+0.044	+0.375	<.001	<.001	3	11
STAD	Mitochondrial translation →	+0.071	+0.369	<.001	<.001	3	11
SCLC	Regulation of melanocyte differentiation →	-0.164	-0.385	<.001	.003	3	11
STAD	tRNA 5'-end processing →	+0.053	+0.289	<.001	<.001	3	11
STAD	Mitochondrial respiratory chain complex assembly →	+0.067	+0.402	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,613 associations by consensus.

tRNA 5'-leader removal by DEFB126 expression — STAD

Explore this box plot interactively →