DEFB126

Across TCGA cell cohorts, DEFB126 RNA expression is significantly associated with the go_rna of many other GO terms, with 539 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DEFB126-associated GO terms across cancer lineages are Regulation of lipid biosynthetic process, Regulation of macroautophagy, and Neuropilin signaling pathway. Each is linked with DEFB126 in more than 3 cancer types. Because this analysis shows association rather than direction, both DEFB126-to-partner and partner-to-DEFB126 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lipid biosynthetic process grouped by DEFB126-low versus DEFB126-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB126→partner) and Y-score (partner→DEFB126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of lipid biosynthetic process →	+0.059	+0.044	<.001	.009	3	4
SKIN	Regulation of macroautophagy →	+0.025	+0.353	.006	.006	3	4
SKIN	Neuropilin signaling pathway →	-0.140	-0.423	<.001	<.001	3	4
SKIN	Basal dendrite development →	-0.157	-0.698	.001	.002	3	3
SKIN	Basal dendrite morphogenesis →	-0.157	-0.698	.001	.002	3	3
SKIN	Basal dendrite arborization →	-0.157	-0.698	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 539 associations by consensus.

Regulation of lipid biosynthetic process by DEFB126 expression — CNS

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