DEFB125

Across TCGA patient cohorts, DEFB125 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,103 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB125-associated GO terms across cancer lineages are Telencephalon development, Regulation of double-strand break repair, and Positive regulation of nervous system development. Each is linked with DEFB125 in more than 10 cancer types. Because this analysis shows association rather than direction, both DEFB125-to-partner and partner-to-DEFB125 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telencephalon development grouped by DEFB125-low versus DEFB125-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB125→partner) and Y-score (partner→DEFB125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telencephalon development →	+0.064	+0.069	<.001	<.001	3	11
STAD	Regulation of double-strand break repair →	+0.084	+0.066	<.001	<.001	3	10
STAD	Positive regulation of nervous system development →	+0.057	+0.060	<.001	<.001	3	10
STAD	Nucleus organization →	+0.090	+0.065	<.001	<.001	3	10
STAD	Organic acid catabolic process →	+0.059	+0.066	<.001	<.001	3	9
STAD	Negative regulation of DNA metabolic process →	+0.073	+0.059	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,103 associations by consensus.

Telencephalon development by DEFB125 expression — STAD

Explore this box plot interactively →