DEFB124

Across TCGA patient cohorts, DEFB124 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB124-associated GO terms across cancer lineages are Heart valve development, Semi-lunar valve development, and Positive regulation of apoptotic signaling pathway. Each is linked with DEFB124 in more than 24 cancer types. Because this analysis shows association rather than direction, both DEFB124-to-partner and partner-to-DEFB124 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heart valve development grouped by DEFB124-low versus DEFB124-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB124→partner) and Y-score (partner→DEFB124) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Heart valve development →	+0.081	+0.308	<.001	<.001	3	25
STAD	Semi-lunar valve development →	+0.079	+0.323	<.001	<.001	3	23
STAD	Positive regulation of apoptotic signaling pathway →	+0.064	+0.304	<.001	<.001	3	22
STAD	Regulation of intrinsic apoptotic signaling pathway →	+0.068	+0.301	<.001	<.001	3	22
SCLC	Retina vasculature development in camera-type eye →	+0.125	+0.628	<.001	<.001	3	22
STAD	Actin polymerization or depolymerization →	+0.079	+0.311	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Heart valve development by DEFB124 expression — STAD

Explore this box plot interactively →