DEFB124

Across TCGA cell cohorts, DEFB124 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,013 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DEFB124-associated GO terms across cancer lineages are Positive regulation of chemokine (C-C motif) ligand 5 production, Otic vesicle formation, and Osteoclast development. Each is linked with DEFB124 in more than 3 cancer types. Because this analysis shows association rather than direction, both DEFB124-to-partner and partner-to-DEFB124 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chemokine (C-C motif) ligand 5 production grouped by DEFB124-low versus DEFB124-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB124→partner) and Y-score (partner→DEFB124) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of chemokine (C-C motif) ligand 5 production →	-0.137	-0.296	<.001	.007	3	4
SKIN	Otic vesicle formation →	-0.537	-1.163	.007	.006	3	4
SKIN	Osteoclast development →	+0.101	+1.120	.006	.004	3	4
SKIN	Otic vesicle morphogenesis →	-0.537	-1.163	.007	.006	3	4
SKIN	Bone cell development →	+0.101	+1.120	.006	.004	3	4
BLOOD_Leukemia	Negative regulation of extracellular matrix disassembly →	+0.209	+0.168	.005	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,013 associations by consensus.

Positive regulation of chemokine (C-C motif) ligand 5 production by DEFB124 expression — BLOOD_Leukemia

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