Across TCGA patient cohorts, DEFB121 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,619 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB121-associated GO terms across cancer lineages are Positive regulation of developmental growth, Negative regulation of DNA metabolic process, and Peptide transport. Each is linked with DEFB121 in more than 4 cancer types. Because this analysis shows association rather than direction, both DEFB121-to-partner and partner-to-DEFB121 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB121→partner) and Y-score (partner→DEFB121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Positive regulation of developmental growth →	+0.039	+0.089	<.001	<.001	3	5
STAD	Negative regulation of DNA metabolic process →	+0.048	+0.086	<.001	<.001	3	5
STAD	Peptide transport →	+0.043	+0.164	<.001	<.001	3	5
UCEC	Regulation of ubiquitin-dependent protein catabolic process →	+0.069	+0.092	<.001	<.001	3	5
UCEC	NADH dehydrogenase complex assembly →	+0.073	+0.087	<.001	<.001	3	5
STAD	Regulation of cholesterol efflux →	+0.040	+0.081	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,619 associations by consensus.

Exploration

DEFB121 survival (RNA) · tumor vs normal (RNA) · all DEFB121 data types