DEFB119

Across TCGA patient cohorts, DEFB119 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,721 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB119-associated GO terms across cancer lineages are Electron transport chain, Muscle cell proliferation, and Regulation of peptide transport. Each is linked with DEFB119 in more than 8 cancer types. Because this analysis shows association rather than direction, both DEFB119-to-partner and partner-to-DEFB119 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Electron transport chain grouped by DEFB119-low versus DEFB119-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB119→partner) and Y-score (partner→DEFB119) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Electron transport chain →	+0.057	+0.061	<.001	<.001	3	9
ESCA	Muscle cell proliferation →	+0.048	+0.295	<.001	.001	3	9
STAD	Regulation of peptide transport →	+0.030	+0.164	<.001	<.001	3	8
STAD	Positive regulation of lymphocyte mediated immunity →	+0.035	+0.150	<.001	<.001	3	8
ESCA	Regulation of protein secretion →	+0.036	+0.220	<.001	.005	2	9
ESCA	Smooth muscle cell proliferation →	+0.053	+0.251	<.001	.006	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,721 associations by consensus.

Electron transport chain by DEFB119 expression — UCEC

Explore this box plot interactively →