DEFB118

Across TCGA patient cohorts, DEFB118 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,420 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB118-associated GO terms across cancer lineages are Mitochondrial gene expression, Nucleoside phosphate biosynthetic process, and Iron-sulfur cluster assembly. Each is linked with DEFB118 in more than 9 cancer types. Because this analysis shows association rather than direction, both DEFB118-to-partner and partner-to-DEFB118 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by DEFB118-low versus DEFB118-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB118→partner) and Y-score (partner→DEFB118) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.071	+0.358	<.001	<.001	3	10
STAD	Nucleoside phosphate biosynthetic process →	+0.060	+0.295	<.001	<.001	3	10
ESCA	Iron-sulfur cluster assembly →	+0.067	+0.321	<.001	<.001	3	10
STAD	Mitochondrial respiratory chain complex assembly →	+0.068	+0.329	<.001	<.001	3	10
STAD	Positive regulation of signal transduction by p53 class mediator →	+0.052	+0.271	<.001	<.001	3	9
ESCA	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.072	+0.305	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,420 associations by consensus.

Mitochondrial gene expression by DEFB118 expression — STAD

Explore this box plot interactively →