Across TCGA patient cohorts, DEFB115 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,074 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB115-associated GO terms across cancer lineages are Negative regulation of CD4-positive, alpha-beta T cell activation, tRNA 5'-end processing, and Morphogenesis of embryonic epithelium. Each is linked with DEFB115 in more than 3 cancer types. Because this analysis shows association rather than direction, both DEFB115-to-partner and partner-to-DEFB115 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB115→partner) and Y-score (partner→DEFB115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Negative regulation of CD4-positive, alpha-beta T cell activation →	+0.066	+0.056	<.001	.007	2	4
STAD	tRNA 5'-end processing →	+0.039	+0.082	.001	.001	3	3
STAD	Morphogenesis of embryonic epithelium →	+0.031	+0.056	.001	.001	3	2
STAD	Urogenital system development →	+0.035	+0.053	<.001	.002	3	2
STAD	Retina homeostasis →	+0.029	+0.079	.001	.003	3	2
STAD	Regulation of leukocyte mediated cytotoxicity →	+0.031	+0.056	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,074 associations by consensus.

Exploration

DEFB115 survival (RNA) · tumor vs normal (RNA) · all DEFB115 data types