Across TCGA cell cohorts, DEFB115 RNA expression is significantly associated with the mutation status of many other genes, with 15 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DEFB115-associated genes across cancer lineages are RAB11A, TCF25, and SCAF4. Each is linked with DEFB115 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB115-to-partner and partner-to-DEFB115 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB115→partner) and Y-score (partner→DEFB115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	RAB11A →	+6.357	+0.263	<.001	<.001	3	1
CNS	TCF25 →	+6.357	+0.263	<.001	<.001	3	1
CNS	SCAF4 →	+4.035	+0.112	.006	<.001	3	1
CNS	ALOX15 →	+4.357	+0.131	.004	<.001	3	1
CNS	SPZ1 →	+5.357	+0.197	.001	<.001	3	1
CNS	DDB1 →	+4.772	+0.158	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

DEFB115 survival (RNA) · tumor vs normal (RNA) · all DEFB115 data types