Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, DEFB115 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.
The most reproducible DEFB115-associated genes across cancer lineages are TGIF2LX and TCP11X1. Each is linked with DEFB115 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB115-to-partner and partner-to-DEFB115 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (DEFB115→partner) and Y-score (partner→DEFB115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.