Across TCGA patient cohorts, DEFB110 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEFB110-associated genes across cancer lineages are Epithelial cells and Th2 cells. Each is linked with DEFB110 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB110-to-partner and partner-to-DEFB110 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB110→partner) and Y-score (partner→DEFB110) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.192	-3.000	<.001	.037	2	2
UCEC	Th2 cells →	+0.308	+3.008	.003	.019	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration

DEFB110 survival (RNA) · tumor vs normal (RNA) · all DEFB110 data types