Across TCGA pan-cancer cohorts, DEFB110 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of DEFB110’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where DEFB110 RNA is repressed in tumor relative to normal tissue. In most cancer types DEFB110 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA are the cancer types where DEFB110 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DEFB110 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	III,IV	−0.066	.022	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: DEFB110 RNA expression & survival · all DEFB110 data types