DEFB109D

Across TCGA patient cohorts, DEFB109D RNA expression is significantly associated with the protein abundance of many other proteins, with 9,766 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DEFB109D-associated proteins across cancer lineages are HDGFL3, ANK2, and SASH1_S101. Each is linked with DEFB109D in more than 4 cancer types. Because this analysis shows association rather than direction, both DEFB109D-to-partner and partner-to-DEFB109D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DEFB109D versus HDGFL3 in UCEC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB109D→partner) and Y-score (partner→DEFB109D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HDGFL3 →	+0.513	+0.923	.002	.002	3	5
GBM	ANK2 →	+0.460	+1.228	<.001	.002	3	4
BRCA	SASH1_S101 →	-0.883	-0.928	.005	.003	3	4
BRCA	TANC1_S448 →	-0.891	-1.216	<.001	.001	3	3
COAD	NOLC1_S563 →	-0.885	-0.532	.001	.002	3	3
UCEC	ARHGEF17_T1991 →	+0.812	+1.117	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,766 associations by consensus.

DEFB109D vs HDGFL3 — UCEC

Explore this scatter interactively →