DEFB108D

Across TCGA patient cohorts, DEFB108D RNA expression is significantly associated with the go_rna of many other GO terms, with 1,804 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DEFB108D-associated GO terms across cancer lineages are Regulation of cholesterol efflux, Sterol biosynthetic process, and Cellular response to leucine starvation. Each is linked with DEFB108D in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB108D-to-partner and partner-to-DEFB108D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cholesterol efflux grouped by DEFB108D-low versus DEFB108D-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB108D→partner) and Y-score (partner→DEFB108D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cholesterol efflux →	+0.075	+0.031	<.001	.002	3	2
UCEC	Sterol biosynthetic process →	+0.051	+0.035	<.001	.001	3	2
UCEC	Cellular response to leucine starvation →	+0.110	+0.035	<.001	.001	3	2
STAD	Cholesterol efflux →	+0.062	+0.050	<.001	.002	3	2
KIRC	Carbohydrate homeostasis →	+0.071	+0.016	<.001	.006	2	3
UCEC	ERAD pathway →	+0.084	+0.060	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,804 associations by consensus.

Regulation of cholesterol efflux by DEFB108D expression — STAD

Explore this box plot interactively →