DEFB108D

Across TCGA pan-cancer cohorts, DEFB108D RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated DEFB108D data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher DEFB108D RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DEFB108D expression acts as an unfavorable survival marker.

SKCM, HNSC, and UCEC are the cancer types where DEFB108D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.058	0.757	<.001	54	view →
HNSC	DFS	Tertile	II,III,IV	0.101	0.695	<.001	54	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DEFB108D–SKCM (DFS)

Open the SKCM breakdown →