Across TCGA pan-cancer cohorts, DEFB108C RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated DEFB108C data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DEFB108C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DEFB108C expression acts as an unfavorable survival marker.
KIRC, ESCA, and SKCM are the cancer types where DEFB108C RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.